I'll be in line, just like I was for the iPhone4, iPad1, iPhone 3GS, and iPhone 3G (I was 2 days late to the party on the iPhone 2G).
A) I'm a sucker for shiny new toys
B) Having facetime/skype on the iPad is going to rock (I have family in Europe that I don't see very often [1/year])
C) The misses wants mine, so it gives me an excuse to upgrade