At the moment there's been some breakthroughs such as wiring sensors into the occipital lobes of blind people that enable them to make out very blury shapes and also some headway (DARPA funded research, I think) on implanting sensors in the brain to remote control prosthetic limbs.
That said, I think it's going to take a bit more than another 14 years to get us to the point where there are serious man-machine fusions. Maybe in 2050.
I'm expecting major breakthroughs in gene therapy will come first.
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