Before attempting anything, go read, read and dread, then download some free rom editing suites, a lot of them will have help files that explain certain ways thier individual software handles data changes.
I am sorry to say that like everything there is no real substitute for experience and seat time, lots of editing, analysis, flashing, pulling etc etc.
As for general tuning methology, everyone will tell you the 'best' way , sure there are certain areas you can can concentrate on, everyone will tell you a different route to a close enough eventual point.
Sorry but to explain in depth would take days ;-) its not rocket science, but you do need to understand the effects your 'little' changes have on your 10K motor.
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Boosted V8 hunter
2850 lbs and 375WHP
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