Originally Posted by Xan

Obviously it's only safe as any tune can be safe... Even the OEM tune can cause problems.

I don't think it's worth to have a full discussion on this, but when done with safety in mind, done correctly (correct install and within the limits of what the engine components can handle) and you look at how you can compensate for items that could damage the engine, a supercharger setup like this is a pretty safe bet.

You might not want to take my word for it and I'm not saying you should, feel free to disagree.
But maybe my statements have some more credibility if I told you that I have worked at Jaguar (uk), where my team was responsible for the calibration of the V8 engines, this included the NA and SC engines. So I've spend my fair share tuning engines for performance, safety, mpg and emission. And I know what it takes to break an engine and how to ensure they are reliable...