When troubleshooting a misfire, the best starting point is to use an OBD scanner and look at your long and short term fuel trims.
Also, look at the mode $06 data, as it has misfire counters and you can get a sense if it is common to a cylinder bank. OBD Fusion has a very good diagnostic report that shows all this data.
You might want to also pull the plugs and see if they are all the same.
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