I have the same amp and just finished my install last week. No engine noise luckily.
I ran rca's down the middle, power wire down the drivers side. New speaker wire from amp(under that black foam piece) to crossovers under the seats, to door components. When your wires start to get closer together as they get closer to the amp make sure they don't run parallel next to each other. If they have to cross each other I have always heard to cross them at 90 degrees. I used that bolt to the left of the remote sensor thingy that was talked about in another thread to ground my amp. Used a wire brush in a drill to clean it down to metal.
The head unit is grounded to the wire harness on mine.
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