As previously mentioned, US 129 - 318 turns in 11 miles - South edge of the Smoky Mountain National Park. This one is my favorite in the eastern half of the US. Makes for a great 3 day weekend from Indy. Worth a visit, no matter where you're from.:
I've ridden and driven it probably two dozen times. Midweek is the best. Weekends tend to be a bit crowded. It doesn't have to be as bad as the video makes it seem. But it can be if you get stupid. There are a couple of web sites to buy your pictures after you go, if you run it when they're out taking pics. The semis aren't supposed to be there, but once they get past a certain point there's no way to turn back.