I'm dropped on KW V1 with about 1 finger gap with a 19x10.5 +12 and have had both 255 and 265 up fronts. Not sure if you're talking about fitting the fenders or clearing the suspension, but +22 with stock fenders on 265 will definitely be fine on the outside. Not sure about clearing struts though but I'm assuming it will be fine as well, I have quite a bit of clearance on the inside.
Have about -1.8 camber up front. Running 305/30 in the rear on 19x11 +13 with -3.2 camber but going to straighten that out on my next alignment