Surprisingly, I get better gas mileage not using 7th. The interstate I commute on daily is very hilly which causes you to basically floor it to maintain speed going up a semi-steep hill at 80mph. I find that if I stay in 5th I end up getting better MPG. YMMV.
Also, the FI exhaust in 7th up a big hill is fairly annoying on the inside
Note: On normal roads, I get better gas mileage using 7th. On the hilly interstate is the only place it is worse.