If you have cruise control then yes, Uprev has the capability to run 5 maps, most people get some variation of the same tune ie power, economy, valet, etc, but they are completely independent so you could have them tuned for whatever you wanted.
I know a couple guys who did the C16 thing, all of them are FI tho. The only issue (unless you add a fuel cell) is that you have to drain the tank completely before you fill up with C16 or the tune's going to be off, probably not as serious with NA but I'm sure you'd be running much more aggressive timing, and if the C16 got diluted it might lead to detonation...
All in all tho I really don't know how much extra HP you'd get on a stock motor, for the same cost you could pick up a motordyne M370 and have some gains every day on pump
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